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All eyes turn for a compelling top-flight contest as front-runners Arsenal entertain bottom-placed Wolverhampton Wanderers to the Emirates Stadium.

Confirmed Sides

Arsenal have opted for three changes from the team that suffered a narrow loss at Aston Villa last weekend. William Saliba, Viktor Gyökeres and Gabriel Martinelli all start in the lineup. Martin Ødegaard and Mikel Merino are named on the substitutes' bench, while the Italian defender is not involved. The centre-back returns after sitting out five matches through injury.

Wolves also have made three adjustments to their starting XI following being soundly beaten 4-1 at Molineux by United on Monday evening. The experienced full-back, João Gomes and Hwang Hee-chan come in. Ki-Jana Hoever and Arias drop to the substitutes, while Jean‐Ricner Bellegarde misses out altogether.

Confirmed Lineups

Arsenal: Raya, White, Saliba, Hincapie, Timber, Eze, Zubimendi, Rice, Saka, Gyokeres, Martinelli.
Subs: Arrizabalaga, Odegaard, Gabriel Jesus, Norgaard, Trossard, Madueke, Nwaneri, Merino, Lewis-Skelly.

Wolverhampton Wanderers: Johnstone, Mosquera, Agbadou, Toti Gomes, Doherty, Joao Gomes, Andre Trindade, Krejci, Wolfe, Larsen, Hwang.
Subs: Tchatchoua, Mane, Lopez, Hoever, Chirewa, Arokodare, Arias, Santiago Bueno, Jose Sa.

Match Official: Robert Jones
Video Assistant Referee: John Brooks

The Setup

Welcome! And I mean, let's be honest …

The table tells a stark contrast. Arsenal sit comfortably at the summit of the table, while Wolves prop up the division.

… yet while this will be the 42nd time the Premier League leaders have faced the team at the foot of the entire table – with 30 victories from 41, with seven tied games – which team is responsible for two of the four historical shocks? Why, Wolverhampton Wanderers, that’s who! Therefore, although the Arsenal manager will undoubtedly be anticipating another three points, the Wolves boss must know that underdogs occasionally find the target, and anything is possible. The start is at 8 o'clock in the evening GMT. It’s on!

^{(The other two last-over-first victories in the Premier League era are Oldham’s 1-0 win over Manchester United in March 1993, and Tottenham Hotspur – yeah, a surprising one - beating Liverpool in November 2008.)}